I went on this trip 8 years ago and it was fantastic. There are so many wonderful things to see. Ancient Rome and the Vatican museum are amazing. After the fall of the Roman Empire, the Catholics roamed the Mediterranean area and collected some of the most amazing artifacts. The museum also hosts items presented to the church over the last 2,000 years.
On this trip you will see: Lake Garda [beautiful], Verona, Venice [a must see in this lifetime], the Piazza San Marco, the Basilica of St. Mark, the romantic Bridge of Sighs, Pisa [the tower is really cool... it is actually a church bell tower], Lucca, Florence, San Gimignano [fantastic little city], Siena, Assisi, the magnificent Colosseum, the Pantheon, the Circus Maximus, Arch of Titus, famous Baths of Caracalla, the Arch of Constantine, and much more!
It's a beautiful day in God's world, be sure to see the good.